Vinpocetine is a powerful memory enhancer. It facilitates cerebral metabolism by improving cerebral micro-circulation (blood flow), stepping up brain cell ATP production (ATP is the cellular energy molecule), and increasing utilisation of glucose and oxygen.
Vinpocetine is often used for the alleviation of cerebral circulatory disorders such as memory problems, acute stroke, aphasia (loss of the power of expression), apraxia (inability to coordinate movements), motor disorders, dizziness and other cerebro-vestibular (inner-ear) problems, and headache.
The use of Vinpocetine in treating acute or chronic ophthalmological diseases of various origins has shown visual acuity improving in 70% of the subjects. Vinpocetine also is used in the alleviation of sensorineural hearing impairment.
Gedeon Richter has funded more than one hundred studies on Vinpocetine, often comparing its effect to other smart drugs. The incidence of side effects in humans using the drug orally is usually less than 1% of a study’s participants, with the unwanted effects usually disappearing with continued use. One series of studies that Gedeon Richter conducted involved 882 patients with neurological disorders ranging from stroke to cerebral insufficiency. Significant improvements were found in 62% of the patients. In one of the studies, cerebral insufficiency patients were asked to memorise a list of 10 words. Without Vinpocetine the subjects were able to memorise an average of 6 words. After a month of supplementation the average went up to 10 words. Gedeon Richter promotes Vinpocetine as the only drug that improves cerebral metabolism (glucose and oxygen uptake), tolerance of hypoxia (deficient blood oxygenation), ATP concentration, norepinephrine and Serotonin turnover, and cerebral microcirculation. He also claims that Vinpocetine selectively increases blood flow to the brain, improving blood flow to the impaired area without lowering blood flow to other parts of the body.
As if the medical uses of Vinpocetine were not amazing enough, in one double-blind crossover study, normal healthy volunteers showed incredible short-term memory improvement an hour after taking 40mg of Vinpocetine. The volunteers took a computer-administered short-term memory test called a Sternberg Memory Scanning Test. The volunteers (all women between the ages of 25 and 40) were shown one to three digits on a computer screen, then a moment later were shown a long string of digits. The volunteers then indicated whether any of the first strings appeared in the second long string. The time the volunteers took to remember was then assessed. On a placebo the women took an average of 700 milliseconds to response when the first set contained 3 digits. With Vinpocetine they averaged fewer than 450 milliseconds!
Vinpocetine is a derivative of vincamine, which is an extract of the periwinkle. Although they have many similar effects, Vinpocetine has more benefits and fewer adverse effects than vincamine.
Contra-indications and Precautions: Adverse effects are rare, but include hypotension, dry mouth, weakness, and tachycardia. Vinpocetine has no drug interactions, no toxicity, and is generally very safe.